Dysbiosis of The Gut and Blood Linked with Inflammation and Heart Disease

French researchers link dysbiosis of the blood with adverse cardiovascular events   Watch this video below to learn more!   CHOLESTEROL AND HEART DISEASE: BACTERIA ARE PARTOF THE STORY Despite the huge progress in … [Read more...]

Diet, Gut Microbiota and Immune Responses Through the Lens of Short Chain Fatty Acids (SCFA)

Virtually every immune-mediated disease is on the rise, from asthma to allergies to various autoimmune diseases. Historically, scientists have blamed excessive hygiene as a root cause of an over-vigilant immune system. This hygiene … [Read more...]

Beyond Leptin Resistance: the many ways leptin prevents fat burning

WHAT IS LEPTIN? In 1994, Jeffrey Friedman, MD, PhD, and his colleagues at Rockefeller University discovered this peptide and named it appropriately “leptin,” from the Greek word for thin, leptos. This discovery and the awareness that one … [Read more...]

Feeling ‘Gutsy?’ There’s a Lot to Swallow…

Developments surrounding our understanding of the intestine and it’s associated microflora are contending to be the most exciting research topics of the decade. Almost weekly cutting-edge research emerges in this arena, furthering … [Read more...]

In Defense Of HDL: Lancet Suggests HDL is Unprotective?

HDL Under-siege Last Thursday the Lancet published a multi-author meta analysis that is challenging the notion that increased HDL cholesterol levels offer protection against myocardial infarction (MI)(Voight 2012). Using genome-wide … [Read more...]

Weight Regain After Dieting Is Due to Gut Hormones, Inflammation

Guts over glory—why diets fail. Nature Medicine,

With or without the 5 pound microbial mass residing in our inner-tube of life, the gut and it’s related incretin hormones comprise a powerful metabolic organ. The May 2012 issue of Diabetologia discuses the progress that has occurred in the … [Read more...]

Delayed Gluten Exposure During Infancy Augments Later Life Immunological Response and Autoimmunity to Gluten

Bacteroides fragilis activates Treg cells

dysfunctional cross talk between innate and adaptive immunity…..could be influenced by the timing of gluten introduction into the diet.... and composition of the GI microbiota," notes Sellitto et al 2012. Alessio Fasano's group at … [Read more...]

Time to Rethink Toxicity, Says a New Endocrine Society Report

EDCs can mimic estrogen, pictured below On March 14th the Endocrine Society published a collaborative, 78 page report which elucidates an emerging paradigm shift in the field of environmental toxicology. The obsolete thinking that “the … [Read more...]

New Associations Between H. pylori Colonization and Markers of Blood Sugar Dysregulation

A research team from New York found a positive correlation between H. pylori status, increasing age, body mass index and glycated hemoglobin (HbA1c) levels (Chen 2012). That is to say elevated levels of HbA1c and H. pylori were more … [Read more...]

New Mechanisms Linking Dysbiosis to gastroesophageal reflux disease (GERD) and Barrett’s Esophagus

Dysbiosis leads to inflammation and bacterial penetration

Is dysbiosis of the upper-GI tract to blame for esophageal gastroesophageal reflux disease (GERD) and it's related conditions, Barrett's esophagus and adenocarcinoma? For the past four years we've known that individuals with GERD have … [Read more...]

Industrialization and Manufacturing are “Metabolically Expensive”

endocrine-disrupting chemicals (EDCs) disrupt our metabolic physiology

Toxic Compounds from Chinese Manufacturing Found in Food are Contributing to Excess Body Weight and Hormonal Dysfunction and Satiety Synthetic endocrine-disrupting chemicals (EDCs) disrupt our metabolic physiology and are ubiquitous, that … [Read more...]