BINGE DRINKING CAUSES LEAKY GUT, RAISING LEVELS OF BACTERIA AND ENDOTOXIN IN THE BLOOD

Binge drinking—having more than four drinks—not only stresses your liver. A recent study revealed it affects your liver’s sister organ, the gut, as well. Alcohol is a known inducer of gut permeability; that is, it causes leaky gut. More … [Read more...]

Weight Regain After Dieting Is Due to Gut Hormones, Inflammation

Guts over glory—why diets fail. Nature Medicine,

With or without the 5 pound microbial mass residing in our inner-tube of life, the gut and it’s related incretin hormones comprise a powerful metabolic organ. The May 2012 issue of Diabetologia discuses the progress that has occurred in the … [Read more...]

The Role of Methyl Donor and Choline Deficiency in Lipid Synthesis: SREBP-1

SAMe and phosphatidylcholine deficiency stimulate cholesterol and lipid synthesis

Low Cellular Availability of Methyl Group donors and Choline Stimulate an Alternative Lipid Synthetic Pathway: The role of SREBP-1 in Lipid Biosynthesis ....nutritional or genetic conditions limiting SAMe or PC production may activate … [Read more...]

The Gut-Brain Axis Regulates Appetite and Satiety

The postprandial release of glucagon-like peptide 1 (GLP-1) from the intestinal neuroendocrine cells leads to reduced appetite and inhibition of food intake. Vickers et al. note, "GLPs are known to modify food intake, increase satiety, … [Read more...]