Published on March 5th 2012, University of San Diego researchers discovered that ingestion of dietary trans fats are associated with increased aggressive behavior after adjusting for confounding variables such as age, education, smoking and alcohol use. Aggression was quantified in the mixed gender study cohort of 1018 using several scientifically validated assessment techniques, including the Overt Aggression Scale Modified-Aggression sub scale (OASMa).
It’s been proposed that ingestion of trans fats lead to decreased synthesis of the neuroprotective omega-3 fatty acid docosahexaenoic acid (DHA) and increased production of inflammatory and oxidative mediators that cross the blood-brain-barrier. The above combination of cellular imbalances may decrease neurological function, leading to aggressive behavior and depression.
This was an observational study that did not utilize objective assessment tools such as RBC fatty acid or plasma phospholipid trans fats. Additionally trans fat consumption was estimated by dietary recall.
Published online 2012 March 5.
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